The goal of this paper is to introduce the promotion of technology-based entrepreneurship as an engine for Mediterranean economic growth, with an emphasis on the role of entrepreneurs. Without avoiding or undermining current problems or challenges, this document takes a look at the Mediterranean Basin free of stereotypes and from a constructive viewpoint. Hence it applies to the Mediterranean the words spoken by Shimon Peres when he received the Nobel Peace Prize together with Yasser Arafat and Yitzhak Rabin in 1994: “A Middle East that is not a killing field but a field of creativity and growth.”